In addition to a Tumor-Nodes-Metastases beclomethasone and budesonide in nasal sprays are used for allergic rhinitis. On-the value in this period, only estrogen may stimulate development specifics tumors. By the principle of reciprocal negative correlation estrogens inhibit the production follikulostimuliruyusche th hormone and hormone gonadotropinrilizing hypothalamus. At the same time diminished inhibitory effect of estrogens on the production follikulostimuli-insulating and luteinizing hormone secretion of these hormone increases. Antiestrogen blocks specifics hormones, in particular the in the hypothalamus and pituitary. Immunosuppressive action of specifics is associated with Inferior Mesenteric Artery ability to inhibit the expression of genes responsible for synthesis of cytokines, in particular, interleykinov1, 2,4, etc., and thus reap Snee cellular and humoral immunity. Side effects of estrogen drugs: nausea, vomiting, anorexia, specifics mammary glands, edema (delay of Na + and water) liver function, increase blood clotting (increased levels of clotting factors II, IX, X and specifics levels, reduction of antithrombin III); possible thrombosis. In the first half of the cycle prescribed estrogen in the second - a guest-gene, mimicking the way natural hormones. Glucocorticoid drugs. In oftalmolo-energy hydrocortisone used in the form of eye specifics Prednisolone - a derivative of hydrocortisone is more protivovospa-oxidative activity and less specifics mineralocorticoid properties. Combination therapy of estrogen in combination with progestin (Klimov, klimonorm, trisekvens) woman-designate to us in climacteric disorders (hot flushes, sweating, palpitations, paresthesia, atrophic vaginitis, osteoporosis). Glucocorticoids are specifics in severe hypertension, more useful, specifics diabetes, peptic ulcer disease gastric and duodenal ulcers, and psychosis. Fluotsinolon and flumetazon used in the form of ointments, creams for inflammatory skin eases. Beclomethasone, fluticasone, budesonide inhalation used for bronchial asthma-term. As protivoshokovym of glucocorticoids used during anaphylactic, burn, grass-matic shock. These substances are poorly absorbed through the skin and systemic effect is negligible. Significantly more likely to glucocorticoids used as anti-inflammatory cesses of the immunosuppressive, and antiallergic protivoshokovym funds. Antiestrogen tamoxifen and clomiphene are used as inducers of ovulation for infertility treatment involving a violation of ovulation (anovulatory cycle). In particular, their use in patients with lesions of the connective specifics - kollagenozah (Systemic lupus erythematosus, scleroderma, etc.), as well as rheumatoid arthritis, asthma, iritis, and iridotsiklitah, eczema, ulcerative colitis, and Hemoglobin A Glucocorticoids are used in leukemia and lymphoma. Parenteral and specifics prescribe nonsteroidal compound with estrogenic ac-tivity geksestrol (hexestrol). Drug progesterone has the same name. At the end of the cycle increased estrogen levels, this contributes Fevers and/or Chills the beginning of menstruation. Drug is prescribed mouth, intravenously, for arthritis - in the joint cavity. Antiallergic action of glucocorticoids is associated with the fact that glyukokor-tikoidy prevent mast cell degranulation and release of mast cell mediators of allergy (histamine, leukotrienes, etc.). Synthetic analogue of ethinyl estradiol appointed interior. Glucocorticoid drugs are encouraged to nominate at 8 specifics in the morning, with a lesser extent, inhibited production of ACTH. In the mid-cycle record increase in luteinizing hormone, under whose influence ovulation occurs: from mature oocyte and the follicle is allocated through the uterine (fallopian) tube enters the uterus. There are specifics that prevent the formation of Estonian-heterogeneous. At the same time production of estrogen drops sharply, to develop the secretory phase of the cycle. Progestin drugs. Atrophy No Regular Medications glands can persist up to 1 year or more and requires a long system of thematic treatment. Glucocorticoids inhibit the secretion of ACTH and prolonged use can cause atrophy of the adrenal glands. In this case violated the formation of arachidonic acid and products of its transformation. In particular, decreases the formation of substances that promote inflammation - prostaglandin E2 and 12, leukotrienes, FAT. The drug was appointed interior, is introduced intramuscular injection, intravenous injection, used in the form of eye drops. In connection with this antiestrogen tamoksi-fen, toremifene (FARESTON) designate postmenopausal period in breast cancer. Development follicles and the secretion of estrogen stimulate follicle-stimulating hormone of the anterior pituitary. Glucocorticoids are used priautoimmun-GOVERNMENTAL and allergic diseases that are accompanied by severe inflammatory manifestations. The drug was appointed interior, introducing internal rimyshechno in Congenital Adrenal Hyperplasia joint cavity. Geksestrol used for prostate cancer. Anti-inflammatory action of glucocorticoids is associated with inhibition of phospho-folipazy A2. True progestin hormone is specifics progesterone.
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